A monoterpene glycoside that has analgesic and anti-inflammatory actions in mice

Paeoniflorin – 500 mg

Brand:
Cayman
CAS:
23180-57-6
Storage:
-20
UN-No:
Non-Hazardous - /

Paeoniflorin is a monoterpene glycoside first isolated from the roots of peony. It has diverse cellular actions, including modulating NMDA and TRPV1 receptors.{31755,31756} Paeoniflorin is reported to inhibit testosterone synthesis and stimulate aromatase activity.{31757} It also reduces inflammatory signaling by inhibiting p38 MAP kinase and blocks pancreatic cancer cell apoptosis by suppressing MMP-9 and ERK signaling.{31758,31759,31760} Presumably through some of these actions, paeoniflorin has analgesic and anti-inflammatory actions in mice.  

 

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Description

A monoterpene glycoside that has analgesic and anti-inflammatory actions in mice

Formal name: (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl β-D-glucopyranoside

Synonyms:  NSC 178886

Molecular weight: 480.5

CAS: 23180-57-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Glycosides||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|ERK/MAPK Signaling||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Pain Research

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