Description
An HDAC inhibitor (IC50s = 21 nM, 100 nM, and 11.48 µM for HDAC1, 2, and 3, respectively); possesses six6-fold extended half-life for binding on HDAC2 compared to HDAC1 (381 min vs. 65 min); rescues the memory defects associated with p25 induced neurodegeneration in contextual fear conditioning in a CK-p25 mouse model of neurodegeneration
Formal name: N-[2-amino-5-(4-pyridinyl)phenyl]-1-pyrrolidinecarboxamide
Synonyms:
Molecular weight: 282.3
CAS: 1404562-17-9
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Small Molecule Inhibitors|Deacetylases||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Neurodegenerative Disorders
