Description
A bivalent Smac mimetic that antagonizes cIAP1, cIAP2, and XIAP at nanomolar concentrations; causes caspase activation, PARP cleavage, and NF-κB activation in breast cancer cells
Formal name: (2S,2’S)-N,N’-[(6,6′-difluoro[2,2′-bi-1H-indole]-3,3′-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)]-propanamide
Synonyms: TL-32711
Molecular weight: 806.9
CAS: 1260251-31-7
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|NF-κB Signaling||Research Area|Cancer|Transcription Factors|NF-κB||Research Area|Immunology & Inflammation
