A selective

Bafilomycin C1 – 5 mg

Brand:
Cayman
CAS:
88979-61-7
Storage:
-20
UN-No:
Non-Hazardous - 3462 / 6.1

Bafilomycin C1 is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases).{20718} It blocks these pumps in mammalian, plant, or fungal cells, preventing proton transport and compartment acidification.{20718} Bafilomycin C1 has been shown to have angiostatic activity in the chick chorioallantoic membrane assay.{31293} It has also been used, when coupled to cellulose, to purify V-ATPases.{31294}  

 

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Description

A selective, reversible inhibitor of V-ATPases in mammalian, plant, or fungal cells

Formal name: 2E-butenedioic acid-1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl] ester

Synonyms:  2-Demethyl-2-methoxy-24-methyl-hygrolidin|L-681,110A1

Molecular weight: 720.9

CAS: 88979-61-7

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|ATPases||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area

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