A potent TP receptor agonist; induces human platelet aggregation with EC50 values of 0.34 and 0.17 nM at pH 7.4 and pH 6.0

I-BOP – 500 µg

Brand:
Cayman
CAS:
128719-90-4
Storage:
-20
UN-No:
De Minimis - 1170 / 3

I-BOP is a potent agonist of TP receptor-mediated platelet aggregation and vascular smooth muscle contraction.{3336} I-BOP induces human platelet aggregation with EC50 values of 0.34 nM and 0.174 nM at pH 7.4 and pH 6.0, respectively.{80}  

 

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SKU: 19600 - Category:

Description

A potent TP receptor agonist; induces human platelet aggregation with EC50 values of 0.34 and 0.17 nM at pH 7.4 and pH 6.0, respectively

Formal name: [1S-[1α,2α(Z),3β(1E,3S*),4α]]-7-[3-[3-hydroxy-4-(4-iodophenoxy)-1-butenyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid

Synonyms: 

Molecular weight: 512.4

CAS: 128719-90-4

Purity: ≥95%

Formulation: A solution in ethanol

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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