A stable isomer of 15(S)-HETE that elicits contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of PC-3 cells

(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic Acid – 1 mg

Brand:
Cayman
CAS:
339534-01-9
Storage:
-20
UN-No:
De Minimis - 1170 / 3

(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid is a stable isomer of 15(S)-HETE (Item No. 34720), a major arachidonic acid metabolite from the 15-lipoxygenase pathway.{31168} (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid elicits concentration-dependent contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of hormone-independent prostate carcinoma PC-3 cells.{31168}  

 

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Description

A stable isomer of 15(S)-HETE that elicits contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of PC-3 cells

Formal name: 15R-hydroxy-5Z,11Z-eicosadien-13-ynoic acid

Synonyms:  HETE Analog 1

Molecular weight: 320.5

CAS: 339534-01-9

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/ Epoxy/Oxo Eicosanoids||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Cardiovascular System|Vasculature|Vasoconstriction||Research Area|Lipid Biochemistry

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