A natural red bacterial pigment that has antibiotic

Prodigiosin – 500 µg

Brand:
Cayman
CAS:
82-89-3
Storage:
-20
UN-No:
Non-Hazardous - /

Prodigiosin is a natural red bacterial pigment that has antibiotic, antitumor, and immunosuppressant properties.{31059} It blocks T cell proliferation at a concentration of 30 ng/ml, by interfering with IL-2 receptor expression.{31056} Prodigiosin induces apoptosis in cancer cells by diverse mechanisms and rescues deficient p53 signaling.{31060,31057,31058} Prodigiosin derivatives can uncouple vacuolar H+-ATPase and inhibit osteoclast function.{31061} Prodigiosin is cytolytic against the red tide dinoflagellate Cochlodinium at very low concentrations (1 ppb), suggesting an application in controlling algal blooms.{31059}  

 

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Description

A natural red bacterial pigment that has antibiotic, antitumor, and immunosuppressant properties; blocks T cell proliferation at a concentration of 30 ng/ml, by interfering with IL-2 receptor expression; induces apoptosis in cancer cells by diverse mechanisms and rescues deficient p53 signaling

Formal name: 4-methoxy-5-[(5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl]-2,2′-bi-1H-pyrrole

Synonyms:  BRN 4526727|NSC 47147

Molecular weight: 323.4

CAS: 82-89-3

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|p53 Signaling||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Immunosuppressants||Research Area|Infectious Disease|Bacterial Diseases

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