A potent

Bafilomycin D – 1 mg

Brand:
Cayman
CAS:
98813-13-9
Storage:
-20
UN-No:
Non-Hazardous - /

The bafilomycins are fungal plecomacrolide antibiotics with a 16-membered lactone ring. They inhibit the growth of Gram-positive bacteria and fungi.{20718,20778} Bafilomycin D is a potent inhibitor of vacuolar H+ ATPases (V-ATPases) that inhibits the V-ATPase from the fungus N. crassa with an IC50 value of approximately 2 nM.{20778} It is about 1,000-fold less effective against the K+-dependent ATPase of E. coli.{20778}  

 

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Description

A potent, selective inhibitor of the V-ATPase from N. crassa with an IC50 value of approximately 2 nM

Formal name: (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(1S,2R,3S,5E,7S,8R)-2,8-dihydroxy-1,3,7,9-tetramethyl-4-oxo-5-decen-1-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-oxacyclohexadeca-3,5,11,13-tetraen-2-one

Synonyms: 

Molecular weight: 604.8

CAS: 98813-13-9

Purity: ≥99%

Formulation: A powder

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|ATPases||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area

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