A potent inhibitor of activated LIMK1 and LIMK2 (IC50s = 5 and 6 nM

BMS-3 – 25 mg

Brand:
Cayman
CAS:
1338247-30-5
Storage:
-20
UN-No:
Non-Hazardous - /

BMS-3 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 (IC50s = 5 and 6 nM, respectively).{32445} It is used to study the role of activated LIMK isoforms in the signaling of Rho family GTPases to cytoskeletal proteins, including cofilin and tubulin.{32443,32444,32446}  

 

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Description

A potent inhibitor of activated LIMK1 and LIMK2 (IC50s = 5 and 6 nM, respectively)

Formal name: N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-cyclopropanecarboxamide

Synonyms: 

Molecular weight: 429.3

CAS: 1338247-30-5

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|Other Serine/Threonine Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cytoskeleton & Motor Proteins

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