A potent inhibitor of HCV infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 µM); displays good pharmacokinetics in mice when delivered intraperitoneally

CAY10704 – 10 mg

Brand:
Cayman
CAS:
101784-44-5
Storage:
-20
UN-No:
De Minimis - 1170 / 3

CAY10704 is a potent inhibitor of hepatitis C virus (HCV) infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 µM).{30619} It displays good pharmacokinetics in mice when delivered intraperitoneally, with preferential liver distribution without significant hepatotoxicity.{30619} CAY10704 is selective for HCV over dengue virus (EC50 = 4.62 µM).{30619}  

 

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Description

A potent inhibitor of HCV infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 µM); displays good pharmacokinetics in mice when delivered intraperitoneally, with preferential liver distribution without significant hepatotoxicity

Formal name: 1-[bis(4-chlorophenyl)methyl]-4-methyl-piperazine

Synonyms: 

Molecular weight: 335.3

CAS: 101784-44-5

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Antivirals||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Hepatitis

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