A nonpeptide ligand that releases IGF-1 from IGFBP (Kis = 1-24 nM for the six human subtypes of IGFBP); used to assess the role of IGF-1 in cells and animals

NBI 31772 – 10 mg

Brand:
Cayman
CAS:
374620-70-9
Storage:
-20
UN-No:
Non-Hazardous - /

NBI 31772 is a nonpeptide ligand that releases insulin-like growth factor-1 (IGF-1) from its binding protein (IGFBP; Kis = 1-24 nM for the six human subtypes of IGFBP).{33124,33126} As the released IGF-1 is biologically active, NBI 31772 is used to assess the role of IGF-1 in cells and animals, including in neuron survival, skeletal muscle regeneration, and glucose homeostasis.{33125,33127,33128}  

 

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Description

A nonpeptide ligand that releases IGF-1 from IGFBP (Kis = 1-24 nM for the six human subtypes of IGFBP); used to assess the role of IGF-1 in cells and animals

Formal name: 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid

Synonyms: 

Molecular weight: 341.3

CAS: 374620-70-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cell Biology|Cell Signaling|Growth Factor Receptors||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Neuroscience

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