An aromatic hydrazine-containing fluorophore that reacts with aldehydes or ketones for fluorescent labeling; acts as a sensor for oxidative stress by detection of carbonylated biomolecules in live cells; ex/em = 365/430-550 nm; produces a red shift in emission upon hydrozone formation; displays a large Stokes shift of approximately 195 nm

Coumarin hydrazine – 1 mg

Brand:
Cayman
CAS:
113707-87-2
Storage:
-20
UN-No:
Non-Hazardous - /

Coumarin hydrazine is an aromatic hydrazine-containing fluorophore that reacts with aldehydes or ketones for fluorescent labeling.{30349} At neutral pH, coumarin hydrazine reacts faster with aldehydes than coumarin hydrazide to form hydrazones. Coumarin hydrazine acts as a fluorogenic sensor in live cells to detect carbonylated biomolecules that occur following oxidative stress.{38469} It displays an excitation maximum of 365 nm, produces a red shift in emission from approximately 430-550 nm upon hydrozone formation, and displays a large Stokes shift of approximately 195 nm.  

 

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Description

An aromatic hydrazine-containing fluorophore that reacts with aldehydes or ketones for fluorescent labeling; acts as a sensor for oxidative stress by detection of carbonylated biomolecules in live cells; ex/em = 365/430-550 nm; produces a red shift in emission upon hydrozone formation; displays a large Stokes shift of approximately 195 nm

Formal name: 7-hydrazinyl-4-methyl-2H-1-benzopyran-2-one

Synonyms:  ​CH-1|7-hydrazino-4-methyl Coumarin|BzCH

Molecular weight: 190.2

CAS: 113707-87-2

Purity: ≥90%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes

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