A third-generation

Ceftriaxone (sodium salt hydrate) – 1 g

Brand:
Cayman
CAS:
104376-79-6
Storage:
-20
UN-No:
Non-Hazardous - /

Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls.{27903,29387,25856} It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.{30535}  

 

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Description

A third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls; increases EAAT-2 pump expression in the CNS and reduces glutamatergic toxicity in both in vitro and in vivo models

Formal name: (6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, disodium salt, hemiheptahydrate

Synonyms:  Ceftriaxone disodium hemiheptahydrate|Ro 13-9904|Rosihlitazone

Molecular weight: 661.6

CAS: 104376-79-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Cephalosporins||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Neuroscience

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