Description
A potent activator of PKA (Ki = 30 nM) that is selective for PKA over PKG (Ki = 10 µM); resistant to degradation by cyclic nucleotide phosphodiesterases, displays good cell permeability, and prevents the aggregation of platelets stimulated with thrombin
Formal name: 5,6-dichloro-1-[3,5-O-[(S)-mercaptophosphinylidene]-β-D-ribofuranosyl]-1H-benzimidazole, monosodium salt
Synonyms: Sp-5,6-DCI-cBIMPS
Molecular weight: 419.1
CAS: 142439-96-1
Purity: ≥99%
Formulation: A crystalline solid
Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Cell Biology|Cell Signaling|cAMP Signaling||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis
