A central second messenger in cell signaling

Cyclic AMP – 1 g

Brand:
Cayman
CAS:
60-92-4
Storage:
-20
UN-No:
Non-Hazardous - /

Cyclic AMP (cAMP) is a central second messenger in cell signaling, propagating signals from receptors to downstream pathways. It is generated from ATP by several adenylate cyclase enzymes, which are modulated by G protein-coupled receptors.{16830} cAMP activates protein kinase A and the exchange proteins activated by cAMP (Epac1 and Epac2), which are nucleotide exchange factors for the Rap family of GTPases.{20516,23361} cAMP is degraded to AMP by cyclic nucleotide phosphodiesterases.{22521}  

 

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Description

A central second messenger in cell signaling, propagating signals from receptors to downstream pathways; generated from ATP by several adenylate cyclase enzymes, which are modulated by G protein-coupled receptors

Formal name: cyclic 3′,5′-(hydrogen phosphate) adenosine

Synonyms:  Adenosine 3′,5′-cyclic monophosphate|cAMP|Cyclic adenosine monophosphate|NSC 143670|NSC 94017

Molecular weight: 329.2

CAS: 60-92-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Cell Biology|Cell Signaling|cAMP Signaling

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