A cyclic thiopeptide antibiotic first isolated from S. bernensis; inhibits protein biosynthesis in Gram positive bacteria through binding with ribosomal subunits; induces the transcriptional activator TipA in Streptomyces

Berninamycin A – 5 mg

Brand:
Cayman
CAS:
58798-97-3
Storage:
-20
UN-No:
Non-Hazardous - /

Berninamycin A is a cyclic thiopeptide antibiotic first isolated from S. bernensis.{30218} It inhibits protein biosynthesis in Gram positive bacteria through binding with ribosomal subunits.{30218,30219} Cyclic thiopeptide antibiotics, including berninamycin A, induce the transcriptional activator TipA in Streptomyces.{30217}  

 

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Description

A cyclic thiopeptide antibiotic first isolated from S. bernensis; inhibits protein biosynthesis in Gram positive bacteria through binding with ribosomal subunits; induces the transcriptional activator TipA in Streptomyces

Formal name: L-threonyl-2-[(1Z)-1-amino-1-propen-1-yl]- 5-methyl-4-oxazolecarbonyl-2,3-didehydroalanyl-3-methyl-L-threonyl-2-(1-aminoethenyl)- 5-methyl-4-oxazolecarbonyl-2,3-didehydroalanyl-6-[2-(1-aminoethenyl)- 4-oxazolyl]-5-(4-carboxy-2-thiazolyl)-2-pyridinecarbonyl-2,3-didehydroalanyl-2,3-didehydro-alaninamide (7→1)-lactam

Synonyms: 

Molecular weight: 1,146.10

CAS: 58798-97-3

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Peptides||Product Type|Biochemicals|Small Molecule Activators|Transcription Factors & Coactivators||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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