A diamidine that is cytotoxic to protozoa; affects a variety of enzymes and modulates interactions between nucleic acids and proteins; inhibits diamine oxidase with a Ki value of 13 nM; enhances the enzymatic activity of ACE2

Diminazene (aceturate) – 5 g

Brand:
Cayman
CAS:
908-54-3
Storage:
22
UN-No:
Non-Hazardous - /

Diminazene is a diamidine that is cytotoxic to protozoa, including Trypanosoma, Babesia, and Cytauxzoon.{30410,30407} Diamidines, including diminazene, affect a variety of enzymes and modulate interactions between nucleic acids and proteins.{30408} Diminazene inhibits diamine oxidase with a Ki value of 13 nM.{30408} In Trypanosoma, transport proteins are important in the effectiveness of diminazene.{30411} In rats and in vitro, diminazene enhances the enzymatic activity of angiotensin-converting enzyme 2.{30412}  

 

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Description

A diamidine that is cytotoxic to protozoa; affects a variety of enzymes and modulates interactions between nucleic acids and proteins; inhibits diamine oxidase with a Ki value of 13 nM; enhances the enzymatic activity of ACE2

Formal name: 4,4’-(1-triazene-1,3-diyl)bis[benzenecarboximidamide] compd. with N-acetyl-glycine (1:2)

Synonyms: 

Molecular weight: 515.5

CAS: 908-54-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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