A high-affinity

Carazolol – 100 mg

Brand:
Cayman
CAS:
57775-29-8
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Carazolol is a high-affinity, lipophilic, non-selective ligand of the β-adrenergic receptors (Kis = 0.114 and 0.4 nM for β2- and β3-adrenoceptors, respectively).{30279,30277,30275} It acts as a receptor antagonist (beta blocker) or inverse agonist for β1 and β2 receptors but functions as an agonist at the β3-adrenergic receptor.{30277,30275,30278,30276}  

 

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Description

A high-affinity, lipophilic, non-selective ligand of the β-adrenergic receptors (Kis = 0.114 and 0.4 nM for β2- and β3-adrenoceptors, respectively); acts as a receptor antagonist (beta blocker) or inverse agonist for β1 and β2 receptors but functions as an agonist at the β3-adrenergic receptor

Formal name: 1-(9H-carbazol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol

Synonyms:  (±)-Carazolol|BM 51052

Molecular weight: 298.4

CAS: 57775-29-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Receptor Pharmacology|Inverse Agonists||Research Area|Cardiovascular System|Cardiovascular Diseases||Research Area|Cardiovascular System|Heart|Arrhythmia

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