A selective β1-adrenergic receptor antagonist (log KDs = -8.21

Betaxolol (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
63659-19-8
Storage:
-20
UN-No:
Non-Hazardous - /

Betaxolol is a selective β1-adrenergic receptor antagonist (log KDs = -8.21, -7.38, and -5.97 for β1, β2, and β3, respectively).{25151} This beta-blocker has been used to reduce intraocular pressure in research models of ocular hypertension and glaucoma.{30089,30088,30087} It is also reported to act as a neuroprotective agent in animals, attenuating excitotoxicity or ischemia-induced damage to retinal ganglion cells.{30086}  

 

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Description

A selective β1-adrenergic receptor antagonist (log KDs = -8.21, -7.38, and -5.97 for β1, β2, and β3, respectively) used to reduce intraocular pressure in research models of ocular hypertension and glaucoma

Formal name: 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol, monohydrochloride )

Synonyms:  Kerlone|SL 75212

Molecular weight: 343.9

CAS: 63659-19-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Ophthalmology

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