A cytidine analog that inhibits the reverse transcriptases of HIV1 (IC50 = 45 nM)

Lamivudine – 100 mg

Brand:
Cayman
CAS:
134678-17-4
Storage:
-20
UN-No:
Non-Hazardous - /

Lamivudine is a cytidine analog that inhibits the reverse transcriptases of HIV1 (IC50 = 45 nM), HIV2, and hepatitis B.{29846,22165} It was one of the first approved nucleoside analog reverse transcriptase inhibitors used to treat viral infections. Following prolonged administration, the efficacy of lamivudine is associated with drug resistance, which may be improved through combination treatments.{23834,24185}  

 

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Description

A cytidine analog that inhibits the reverse transcriptases of HIV1 (IC50 = 45 nM), HIV2, and hepatitis B

Formal name: 4-amino-1-[(2R,5S)-2-(hydroxymethyl)1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

Synonyms:  (-)-BCH 189|2’,3’-dideoxy-3’-Thiacytidine|3TC|Epivir-HBV™|Epivir™

Molecular weight: 229.3

CAS: 134678-17-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals|Nucleoside Reverse Transcriptase Inhibitors (NRTIs)||Product Type|Biochemicals|Nucleotides/Nucleosides||Product Type|Biochemicals|Small Molecule Inhibitors|Reverse Transcriptases||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Hepatitis||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS

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