An isomer of valpromide that has been marketed as an anxiolytic and sedative compound; abolishes the activity of MIP synthase in human brain crude homogenates (Ki = 0.18 mM); suppresses electrographic seizures in animal models of status epilepticus

Valnoctamide – 5 mg

Brand:
Cayman
CAS:
4171-13-5
Storage:
-20
UN-No:
Non-Hazardous - /

Valnoctamide is an isomer of the valproic acid amide, valpromide. It has been marketed as an anxiolytic and sedative compound and suppresses neuropathic pain.{29670,29672} Unlike valpromide, valnoctamide is not metabolized to its acid form, valnoctic acid, in vivo and has no teratogenicity.{29670} It abolishes the activity of myo-inositol-1-phosphate synthase in human brain crude homogenates (Ki = 0.18 mM).{21734} Valnoctamide suppresses electrographic seizures in animal models of status epilepticus, suggesting potential applications in managing epilepsy.{29671}  

 

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Description

An isomer of valpromide that has been marketed as an anxiolytic and sedative compound; abolishes the activity of MIP synthase in human brain crude homogenates (Ki = 0.18 mM); suppresses electrographic seizures in animal models of status epilepticus

Formal name: 2-ethyl-3-methyl-pentanamide

Synonyms:  NSC 32363|NSC 34092|Valmethamide|Valoctamidum

Molecular weight: 143.2

CAS: 4171-13-5

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Neuroscience|Behavioral Neuroscience|Anxiety||Research Area|Neuroscience|Pain Research||Research Area|Neuroscience|Seizure Disorders

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