BMS 626529 – 1 mg

Brand:
Cayman
CAS:
701213-36-7
Storage:
-20
UN-No:
Non-Hazardous - /

BMS 626529 is an inhibitor of HIV-1 attachment.{37563,37564} It binds to non-ligand bound HIV-1 gp120 to inhibit HIV-1 interaction with host CD4+ T cells and subsequent HIV-1 binding and cell entry.{37563} BMS 626529 reduces infectivity of laboratory strains and clinical isolates of HIV-1 (EC50s = 0.4-2,000 and 25-2,000 nM, respectively) with cytotoxic concentration (CC50) values greater than 100 μM in a panel of mammalian cell lines.{37564}  

 

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Description

An HIV-1 attachment inhibitor; binds to non-ligand bound HIV-1 gp120 to inhibit HIV-1 interaction with host CD4+ T cells; reduces infectivity of laboratory strains and clinical isolates of HIV-1 (EC50s = 0.4-2,000 and 25-2,000 nM, respectively); not cytotoxic in a panel of mammalian cells (CC50s = >100 μM)


Formal name: 1-(4-benzoyl-1-piperazinyl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-ethanedione

Synonyms: 

Molecular weight: 473.5

CAS: 701213-36-7

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Antivirals|Entry/fusion Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS