Description
An NS3/4A protease inhibitor (Ki = 14 nM for the HCV genotype 1b enzyme); inhibits HCV replication in Huh7 cells (EC50 = 200 nM); inhibits SARS-CoV-2 Mpro (Ki = 1.8 µM); reduces cytopathic effects of SARS-CoV-2 in Vero cells (EC50 = 1.31 µM)
Formal name: (1R,2S,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-3-azabicyclo[3.1.0]hexane-2-carboxamide
Synonyms: Victrelis
Molecular weight: 519.7
CAS: 394730-60-0
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Antivirals|Protease Inhibitors||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Immunology & Inflammation|Pulmonary Diseases|COVID-19||Research Area|Infectious Disease|Viral Diseases|Coronaviruses||Research Area|Infectious Disease|Viral Diseases|Hepatitis
