Member of a complex family of macrocyclic lactones produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus; nematocide and insecticide activity via the potentiation of glutamate and GABA-gated chloride-channel opening; IC50s = 5.3

Milbemycin A3 – 1 mg

Brand:
Cayman
CAS:
51596-10-2
Storage:
-20
UN-No:
Non-Hazardous - /

Milbemycin A3 is a member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus.{26993} As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin A3 is used as a nematocide and insecticide.{26993} The acaricidal and nematocidal activity of a mixture of milbemycin A3 and milbemycin A4 (Item No. 17155) against adult spider mites, spider mite eggs, and C. elegans are reported at IC50 values of 5.3, 41.1, and 9.5 µg/ml.{28380}  

 

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Description

Member of a complex family of macrocyclic lactones produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus; nematocide and insecticide activity via the potentiation of glutamate and GABA-gated chloride-channel opening; IC50s = 5.3, 41.1, and 9.5 µg/ml against adult spider mites, spider mite eggs, and C. elegans when mixed with milbemycin A4

Formal name: (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-methyl-milbemycin B

Synonyms:  Antibiotic B 41A3|Milbemycin α1

Molecular weight: 528.7

CAS: 51596-10-2

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Anthelmintics||Product Type|Biochemicals|Antiparasitics|Anti-ectoparasitics||Product Type|Biochemicals|Ion Channel Modulation|Activators||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Pesticides|Acaricides||Product Type|Biochemicals|Pesticides|Insecticides

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