A chalconoid with anti-inflammatory and anti-tumor activity; suppresses NO and PGE2 synthesis

Cardamonin – 5 mg

Brand:
Cayman
CAS:
19309-14-9
Storage:
-20
UN-No:
Non-Hazardous - /

Cardamonin, isolated from the fruits of Alpinia species, is a chalconoid with anti-inflammatory and anti-tumor activity.{25061,25923} It has been shown to suppress nitric oxide and prostaglandin E2 synthesis, to suppress cyclooxygenase-2 expression, and to inhibit NF-κB signaling.{25061,25923} It can also target the Bcl-2 protein, inducing apoptosis in cancer cells.{25061}  

 

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Description

A chalconoid with anti-inflammatory and anti-tumor activity; suppresses NO and PGE2 synthesis, COX-2 expression, and NF-κB signaling; induces apoptosis in cancer cells

Formal name: (2E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one

Synonyms:  Alpinetin chalcone|Cardamomin

Molecular weight: 270.3

CAS: 19309-14-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Chalcones||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Signaling|NF-κB Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins

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