A diastereomer of tetrahydrofolic acid that is 1

(6S)-Tetrahydrofolic Acid – 25 mg

Brand:
Cayman
CAS:
71963-69-4
Storage:
-20
UN-No:
Non-Hazardous - /

(6S)-Tetrahydrofolic acid is a diastereomer of tetrahydrofolic acid (Item No. 20526), a reduced form of folic acid that serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.{29515} (6S)-Tetrahydrofolic acid is 1,000-fold more active than the (6R) form at promoting the binding of fluorodeoxyuridylate to thymidylate synthase and 600-fold more active as a growth factor of P. cerevisiae.{32161} (6S)-Tetrahydrofolic acid also has a low affinity and high dissociation rate for folate-binding protein.{32160}  

 

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Description

A diastereomer of tetrahydrofolic acid that is 1,000-fold more active than the (6R) form at promoting the binding of fluorodeoxyuridylate to thymidylate synthase and 600-fold more active as a growth factor of P. cerevisiae

Formal name: N-[4-[[[(6S)-2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic acid

Synonyms: 

Molecular weight: 445.4

CAS: 71963-69-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Epigenetics, Transcription, & Translation|Writers

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