A major metabolite of sildenafil; formed via oxidative metabolism of sildenafil by CYP3A4

N-Desmethyl Sildenafil – 10 mg

Brand:
Cayman
CAS:
139755-82-1
Storage:
-20
UN-No:
Non-Hazardous - /

N-Desmethyl sildenafil is a major metabolite of sildenafil (Item Nos. 10008671 | 14008).{29612,29611,42395} N-Desmethyl sildenafil is formed via oxidative metabolism of sildenafil by the cytochrome (CYP) P450 isoforms CYP3A4, CYP3A5, and CYP3A7.{42395}  

 

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Description

A major metabolite of sildenafil; formed via oxidative metabolism of sildenafil by CYP3A4, CYP3A5, and CYP3A7

Formal name: 5-[2-ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one

Synonyms:  UK-103320

Molecular weight: 460.6

CAS: 139755-82-1

Purity: ≥98%

Formulation: A crystalline solid

Application||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Cell Biology|Cell Signaling|cGMP Signaling

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