A brominated derivative of guanosine that has been used to reduce the conformational heterogeneity of RNA to potentially enhance its function; reported to activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects

8-Bromoguanosine – 1 g

Brand:
Cayman
CAS:
4016-63-1
Storage:
-20
UN-No:
Non-Hazardous - /

8-Bromoguanosine is a brominated derivative of guanosine. Purine nucleobases with bromine at position eight are known to preferentially adopt the syn conformation as nucleosides and, thus, can be used to reduce the conformational heterogeneity of RNA to potentially enhance its function.{29473} It is reported to activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects.{29472,29471}  

 

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Description

A brominated derivative of guanosine that has been used to reduce the conformational heterogeneity of RNA to potentially enhance its function; reported to activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects

Formal name: 8-bromo-guanosine

Synonyms:  2-Amino-8-bromo-6-hydroxypurine riboside|NSC 174257|NSC 79211

Molecular weight: 362.1

CAS: 4016-63-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity

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