A brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase; activates cAMP-dependent protein kinase

8-bromo-Cyclic AMP – 10 mg

Brand:
Cayman
CAS:
23583-48-4
Storage:
-20
UN-No:
Non-Hazardous - /

8-bromo-Cyclic AMP is a brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase.{26217,26218} It can activate cAMP-dependent protein kinase, inhibiting growth, decreasing proliferation, increasing differentiation, and inducing apoptosis of cancer cells.{26218}  

 

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Description

A brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase; activates cAMP-dependent protein kinase, inhibiting growth, decreasing proliferation, increasing differentiation, and inducing apoptosis of cancer cells

Formal name: 8-bromo-adenosine cyclic 3′,5′-(hydrogen phosphate)

Synonyms:  8-Bromoadenosine 3′,5′-cyclic monophosphate|8-bromo-cAMP|NSC 171719

Molecular weight: 408.1

CAS: 23583-48-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Signaling|cAMP Signaling

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