A cell-permeable activator of mTOR that can induce cellular LC3-II accumulation in Ac2F cells and has been shown to inhibit autophagy by suppressing the fusion between autophagosomes and lysosomes

MHY1485 – 50 mg

Brand:
Cayman
CAS:
326914-06-1
Storage:
-20
UN-No:
Non-Hazardous - /

MHY1485 is a cell-permeable activator of mTOR that has been shown to increase levels of cellular mTOR Ser2448 and downstream substrate 4E-BP Thr37/46 phosphorylation in rat liver Ac2F cells.{32639} It can induce cellular LC3-II accumulation in Ac2F cells and has been shown to inhibit autophagy by suppressing the fusion between autophagosomes and lysosomes.{32639}  

 

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Description

A cell-permeable activator of mTOR that can induce cellular LC3-II accumulation in Ac2F cells and has been shown to inhibit autophagy by suppressing the fusion between autophagosomes and lysosomes

Formal name: 4,6-di-4-morpholinyl-N-(4-nitrophenyl)-1,3,5-triazin-2-amine

Synonyms: 

Molecular weight: 387.4

CAS: 326914-06-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Cell Biology|Cell Signaling|PI3K/Akt/mTOR Signaling||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|Autophagy

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