An orally-active

Ibutamoren (mesylate) – 5 mg

Brand:
Cayman
CAS:
159752-10-0
Storage:
-20
UN-No:
Non-Hazardous - /

Ghrelin is an endogenous ligand for the growth hormone (GH) secretagogue receptor (GHSR).{7811} Ibutamoren is an orally-active, non-peptidic agonist of GHSR (Kd = 0.4 nM) and, as a result, is a GH secretagogue.{3021,3308} It elevates GH in dogs after oral doses as low as 0.125 mg/kg, without significantly changing plasma levels of aldosterone, luteinizing hormone, thyroxine, or prolactin.{30759}  

 

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Description

An orally-active, non-peptidic agonist of GHSR (Kd = 0.4 nM) and, as a result, is a GH secretagogue; elevates GH in dogs after oral doses as low as 0.125 mg/kg, without significantly changing plasma levels of aldosterone, luteinizing hormone, thyroxine, or prolactin

Formal name: 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4′-piperidin]-1′-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-propanamide, methanesulfonate

Synonyms:  L-163,191|MK-0677

Molecular weight: 624.8

CAS: 159752-10-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Neuroscience|Neuroendocrinology

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