The active metabolite of perindopril

Perindoprilat – 500 µg

Brand:
Cayman
CAS:
95153-31-4
Storage:
-20
UN-No:
Non-Hazardous - /

Perindoprilat is the active metabolite of perindopril, an inhibitor of angiotensin converting enzyme (ACE) that has efficacy against hypertension.{29640} Perindoprilat specifically and competitively inhibits ACE in vitro with IC50 values ranging between 1.5 and 3.2 nM. Elimination of perindoprilat is decreased in the elderly and in patients with heart or renal failure.{29640,29639,29638}  

 

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Description

The active metabolite of perindopril, an ACE inhibitor that has efficacy against hypertension; specifically and competitively inhibits ACE in vitro with IC50 values ranging between 1.5 and 3.2 nM

Formal name: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-carboxybutyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid

Synonyms:  S-9780

Molecular weight: 340.4

CAS: 95153-31-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension

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