An allosteric potentiator of nAChRs and inhibitor of acetylcholinesterase (IC50 = 636-2

Galantamine – 5 mg

Brand:
Cayman
CAS:
357-70-0
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Galantamine is an alkaloid originally isolated from the bulbs and flowers of various Galanthus species. It allosterically potentiates nicotinic acetylcholine receptors, as well as inhibits acetylcholinesterase (IC50 = 636-2,010 nM), thereby promoting acetylcholine activity in the brain.{24085,17054,25283} Galantamine has been used in the clinical treatment of vascular dementia and Alzheimer’s disease symptoms and as a nootropic for other cognitive impairments.{23018,17054,25143}  

 

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Description

An allosteric potentiator of nAChRs and inhibitor of acetylcholinesterase (IC50 = 636-2,010 nM); promotes acetylcholine activity in the brain and used in the clinical treatment of vascular dementia, Alzheimer’s disease, and other cognitive impairments

Formal name: (4aS,6R,8aS)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol

Synonyms:  NSC 100058

Molecular weight: 287.4

CAS: 357-70-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology|Nootropics

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