A synthetic substrate of serine proteases

N-4-Tosyl-L-arginine methyl ester (hydrochloride) – 25 g

Brand:
Cayman
CAS:
1784-03-8
Storage:
-20
UN-No:
Non-Hazardous - /

N-4-Tosyl-L-arginine methyl ester (TAME) is a synthetic substrate of serine proteases, including thrombin, trypsin, chymotrypsin, and kallikreins.{28529,28531,28530} It can be used to evaluate serine proteases from diverse sources.{28532} TAME also binds to and inhibits anaphase-promoting complex, a ubiquitin ligase, in Xenopus egg extract.{28533,28534}  

 

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Description

A synthetic substrate of serine proteases, including thrombin, trypsin, chymotrypsin, and kallikreins; also binds to and inhibits anaphase-promoting complex, a ubiquitin ligase, in Xenopus egg extract

Formal name: N2-[(4-methylphenyl)sulfonyl]-L-arginine, methyl ester, monohydrochloride

Synonyms:  TAME|Tosylarginine methyl ester

Molecular weight: 378.9

CAS: 1784-03-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Small Molecule Inhibitors|Ubiquitin Ligase System||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System

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