Description
A cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM)
Formal name: (2’S,3’R,6’R)-2′,3′-dihydro-3′,6′-dihydroxy-2′-(hydroxymethyl)-2′,4′,6′-trimethyl-spiro[cyclopropane-1,5′-[5H]inden]-7′(6’H)-one
Synonyms: Lampterol|NSC 400979|NSC 626369
Molecular weight: 264.3
CAS: 1149-99-1
Purity: ≥98%
Formulation: A light yellow solid
Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Cancer|Cell Cycle|G1||Research Area|Cancer|DNA Damage and Repair
