A H2S donor; releases H2S in the presence and absence of L-cysteine; increases levels of thiosulfate

4-Hydroxybenzyl isothiocyanate – 5 mg

Brand:
Cayman
CAS:
2086-86-4
Storage:
-20
UN-No:
Non-Hazardous - /

4-Hydroxybenzyl isothiocyanate (HBITC) is a hydrogen sulfide (H2S) originally isolated from S. alba seeds.{48388} It releases H2S in the presence and absence of L-cysteine in a concentration-dependent manner. HBITC (60-80 μM) increases levels of thiosulfate, decreases the mitochondrial membrane potential, and inhibits proliferation of SH-SY5Y human neuroblastoma and U87MG glioblastoma cells.{48389}  

 

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Description

A H2S donor; releases H2S in the presence and absence of L-cysteine; increases levels of thiosulfate, decreases the mitochondrial membrane potential, and inhibits proliferation of SH-SY5Y human neuroblastoma and U87MG glioblastoma cells from 60-80 μM

Formal name: 4-(isothiocyanatomethyl)-phenol

Synonyms:  p-Hydroxybenzyl isothiocyanate|HBITC

Molecular weight: 165.2

CAS: 2086-86-4

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Hydrogen Sulfide Donors||Research Area|Cancer||Research Area|Cell Biology|Mitochondrial Biology

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