Description
A selective PI3Kβ/δ inhibitor (IC50 = 3, 17, and 752 nM for PI3Kβ, δ, and α, respectively); shows no significant binding against a panel of 442 other kinases; inhibits growth of a range of cell lines, with preferential activity in cells with PTEN mutation or deficiency; orally bioavailable
Formal name: 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide
Synonyms:
Molecular weight: 457.5
CAS: 1627494-13-6
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|PI3K||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling
