U-73343 – 1 mg

Brand:
Cayman
CAS:
142878-12-4
Storage:
-20
UN-No:
Non-Hazardous - /

U-73122 (Item No. 70740) is an inhibitor of PLC-dependent processes, however, the mechanism of action remains unclear.{5296,3187,6007} The IC50 values for inhibition of platelet aggregation induced by collagen or thrombin are 0.6 and 5 µM, respectively.{3187} It also exhibits inhibitory activity against HIV-1 integrase with an IC50 value of 7 µM.{3607} U-73343 is a close structural analog of U-73122 that does not inhibit PLC, making it useful as a negative control for PLC inhibition.{5296}  

 

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Description

An inactive analog of U-73122; can be used as a negative control


Formal name: 1-[6-[[(17b)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-2,5-pyrrolidinedione

Synonyms: 

Molecular weight: 466.7

CAS: 142878-12-4

Purity: ≥95%

Formulation: A crystalline solid


Product Type|Biochemicals|Small Molecule Inhibitors|Blood Coagulation Factors||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases