A highly potent inhibitor of the tyrosine kinase activity of EGFR (IC50 = 0.006 nM); inhibits EGFR activity in pancreatic cancer cell lines and induces the differentiation of rat mesenchymal stem cells

Compound 56 – 500 µg

Brand:
Cayman
CAS:
171745-13-4
Storage:
-20
UN-No:
Non-Hazardous - /

Compound 56 is a highly potent inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 0.006 nM).{28435} It has been used to inhibit EGFR activity in pancreatic cancer cell lines and to induce the differentiation of rat mesenchymal stem cells.{28436,28437}  

 

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Description

A highly potent inhibitor of the tyrosine kinase activity of EGFR (IC50 = 0.006 nM); inhibits EGFR activity in pancreatic cancer cell lines and induces the differentiation of rat mesenchymal stem cells

Formal name: N-(3-bromophenyl)-6,7-diethoxy-4-quinazolinamine

Synonyms: 

Molecular weight: 388.3

CAS: 171745-13-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|EGFR/ErbB/HER Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|Growth Factor Receptor Signaling||Research Area|Cell Biology|Cell Signaling|Growth Factor Receptors||Research Area|Cell Biology|Stem Cell Research|Differentiation

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