An inhibitor of BRD4 (Kd = 550 nM; IC50 = 637 nM)

UMB-32 – 10 mg

Brand:
Cayman
CAS:
1635437-39-6
Storage:
-20
UN-No:
Non-Hazardous - /

UMB-32 is an inhibitor of the BET bromodomain BRD4 (Kd = 550 nM; IC50 = 637 nM) and the bromodomain-containing transcription factor TAF1 (Kd = 560 nM) and TAF1L (Kd = 1.3 µM).{27813}  

 

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Description

An inhibitor of BRD4 (Kd = 550 nM; IC50 = 637 nM),TAF1 (Kd = 560 nM), and TAF1L (Kd = 1.3 µM)

Formal name: N-(1,1-dimethylethyl)-2-[4-(3,5-dimethyl-4-isoxazolyl)phenyl]-imidazo[1,2-a]pyrazin-3-amine

Synonyms: 

Molecular weight: 361.4

CAS: 1635437-39-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Chromatin Reader Interactions||Research Area|Epigenetics, Transcription, & Translation|Readers|Bromodomains||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors

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