A ratiometric mass spectrometry probe that can be used for assessing mitochondrial matrix H2O2 concentration in vivo

MitoB – 10 mg

Brand:
Cayman
CAS:
1247025-84-8
Storage:
-20
UN-No:
Non-Hazardous - /

MitoB is a ratiometric mass spectrometry probe that can be used for assessing changes in H2O2 within mitochondria in vivo. MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce a phenol product, MitoP.{27787,27786} Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration.  

 

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Description

A ratiometric mass spectrometry probe that can be used for assessing mitochondrial matrix H2O2 concentration in vivo

Formal name: [(3-boronophenyl)methyl]trip​henyl-phosphonium, monobromide

Synonyms:  MitoBoronic Acid

Molecular weight: 477.1

CAS: 1247025-84-8

Purity: ≥95%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Labeling & Detection||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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