A synthetic H2S donor that can be readily esterified with other moieties

ADT-OH – 10 mg

Brand:
Cayman
CAS:
18274-81-2
Storage:
-20
UN-No:
Non-Hazardous - /

ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. It can be readily esterified with other moieties.{28631} For example, it can be coupled with therapeutics like nonsteroidal anti-inflammatory drugs, as in the generation of ATB-343 (Item No. 13045).{15971} ADT-OH has also been linked with a mitochondria-targeting motif to produce AP-39 (Item No. 17100), which selectively increases mitochondrial H2S levels.{28632} ADT-OH is used both in cells and in animals for comparative studies with derived chimeras.{28632,28633}  

 

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Description

A synthetic H2S donor that can be readily esterified with other moieties, including therapeutics and targeting motifs; used both in cells and in animals for comparative studies with derived chimeras

Formal name: 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione

Synonyms:  ACS1

Molecular weight: 226.3

CAS: 18274-81-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Hydrogen Sulfide Donors||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Oxidative Stress & Reactive Species|Reactive Sulfur|H2S

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