A metabolite of caffeine; scavenges hydroxyl radicals in a cell-free assay at 500 µM; inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes

1,3,7-Trimethyluric Acid – 250 mg

Brand:
Cayman
CAS:
5415-44-1
Storage:
-20
UN-No:
Non-Hazardous - /

1,3,7-Trimethyluric acid is a derivative of uric acid (Item No. 16219) and a metabolite of caffeine (Item No. 14118).{58128} It is formed from caffeine by the cytochrome P450 (CYP) isoform CYP3A4. 1,3,7-Trimethyluric acid (500 µM) scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.{58129}  

 

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Description

A metabolite of caffeine; scavenges hydroxyl radicals in a cell-free assay at 500 µM; inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes

Formal name: 7,9-dihydro-1,3,7-trimethyl-1H-purine-2,6,8(3H)-trione

Synonyms:  8-oxo Caffeine|NSC 11259|NSC 95858|TMU

Molecular weight: 210.2

CAS: 5415-44-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Blood|Erythrocytes & Hemoglobin||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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