A mitochondrial metabolite; catabolized by plasma esterases into carnitine; facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation

Acetyl-L-carnitine (chloride) – 1 g

Brand:
Cayman
CAS:
5080-50-2
Storage:
-20
UN-No:
Non-Hazardous - /

Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine (Item No. 21489) that is catabolized by plasma esterases into carnitine.{27352,27356,27355} Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund’s adjuvant.{43555}  

 

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Description

A mitochondrial metabolite; catabolized by plasma esterases into carnitine; facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis; increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund’s adjuvant at 100 mg/kg

Formal name: 2R-(acetyloxy)-3-carboxy-N,N,N-trimethyl-1-propanaminium, monochloride

Synonyms:  ​L-Acetylcarnitine|ALCAR

Molecular weight: 239.7

CAS: 5080-50-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Carnitines||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Immunology & Inflammation

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