A selective allosteric modulator of M2 receptors that hinders the dissociation of the orthosteric antagonist N-methylscopolamine from the M2 receptor (EC50 = 3 nM)

Dimethyl-W84 (dibromide) – 5 mg

Brand:
Cayman
CAS:
402475-33-6
Storage:
4
UN-No:
Non-Hazardous - /

Dimethyl-W84 is a selective allosteric modulator of the M2 muscarinic acetylcholine receptor.{30736,30737} It hinders the dissociation of the orthosteric antagonist N-methylscopolamine from the M2 receptor with an EC50 value of 3 nM.{30736,30737}  

 

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Description

A selective allosteric modulator of M2 receptors that hinders the dissociation of the orthosteric antagonist N-methylscopolamine from the M2 receptor (EC50 = 3 nM)

Formal name: N1,N6-bis[3-(1,3-dihydro-5-methyl-1,3-dioxo-2H-isoindol-2-yl)propyl]-N1,N1,N6,N6-tetramethyl-1,6-hexanediaminium, dibromide

Synonyms: 

Molecular weight: 736.6

CAS: 402475-33-6

Purity: ≥98%

Formulation: Off-white solid

Product Type|Biochemicals|Receptor Pharmacology|Allosteric Modulators||Research Area|Neuroscience

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