A nonhydrolyzable GTP analog that binds to and irreversibly activates G proteins; potently stimulates adenylate cyclase

Guanylyl Imidodiphosphate (lithium salt) – 5 mg

Brand:
Cayman
CAS:
64564-03-0
Storage:
-20
UN-No:
Non-Hazardous - /

Guanylyl imidodiphosphate is a nonhydrolyzable analog of GTP that can bind to and irreversibly activate G proteins in the presence of Mg2+.{27512} This nucleotide is a potent stimulator of adenylate cyclase.{27510} Guanylyl imidodiphosphate is used in studies of protein synthesis since the process of GTP binding, hydrolysis, and release is essential for the initiation of protein translocation across the endoplasmic reticulum.{27511}  

 

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Description

A nonhydrolyzable GTP analog that binds to and irreversibly activates G proteins; potently stimulates adenylate cyclase

Formal name: 5’-guanylic acid, monoanhydride with imidodiphosphoric acid, tetralithium salt

Synonyms: 

Molecular weight: 545.9

CAS: 64564-03-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Cyclases||Research Area|Cell Biology|Cell Signaling|cAMP Signaling||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis

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