A structural analog of PMA that does not activate PKC; used as a negative control for PMA signaling through PKC

4α-Phorbol 12-myristate 13-acetate – 1 mg

Brand:
Cayman
CAS:
63597-44-4
Storage:
-20
UN-No:
Non-Hazardous - /

Phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) is a phorbol ester that is commonly used to activate certain types of PKC, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.{17804} 4α-PMA is a structural analog of PMA that does not activate PKC.{27366,27365} It is used as a negative control for PMA signaling through PKC.{27365}  

 

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Description

A structural analog of PMA that does not activate PKC; used as a negative control for PMA signaling through PKC

Formal name: tetradecanoic acid, (4aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1aR,1bS,4,4a,5,7aS,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester

Synonyms:  4α-PMA

Molecular weight: 616.8

CAS: 63597-44-4

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Activators|Negative Controls||Research Area|Cell Biology|Cell Signaling

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