Travoprost is the Alcon trade name for fluprostenol isopropyl ester

5-trans Fluprostenol – 5 mg

Brand:
Cayman
CAS:
57968-83-9
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.{9613} Fluprostenol isopropyl ester is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid, fluprostenol.{8839} 5-trans Fluprostenol is an impurity that is routinely found in bulk preparations of fluprostenol in amounts ranging from 1-3%. This impurity occurs in the finished prodrug Travoprost in similar amounts. The pharmacology of 5-trans fluprostenol has not been studied extensively to date.  

 

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Description

Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series PG analog which has been approved for use as an ocular hypotensive drug.{9613} Fluprostenol isopropyl ester is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid, fluprostenol.{8839} 5-trans Fluprostenol is an impurity that is routinely found in bulk preparations of fluprostenol in amounts ranging from 1-3%. This impurity occurs in the finished prodrug Travoprost in similar amounts. The pharmacology of 5-trans fluprostenol has not been studied extensively to date.

Formal name: 9,11,15-trihydroxy-16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5E,13E-dien-1-oic acid

Synonyms:  5,6-trans Fluprostenol

Molecular weight: 458.5

CAS: 57968-83-9

Purity: ≥95%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Pharmaceutical Impurities||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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