A conjugate of biotin and lysine used for derivatization or conjugation to proteins and other molecules with a medium-chain length spacer; also used as an anterograde

Biocytin – 10 mg

Brand:
Cayman
CAS:
576-19-2
Storage:
-20
UN-No:
Non-Hazardous - /

Biocytin is a conjugate of biotin and lysine known formally as ɛ-N-(d-biotinyl)-L-lysine. The addition of lysine to biotin increases the chain length extending from biotin, allowing the synthesis of medium-chain reagents. It also provides terminal carboxyl and amino groups for derivatization or conjugation to proteins and other molecules. Covalent linking reactions typically involve carbodiimide or NHS-ester crosslinking chemistries. Biocytin is also used as an anterograde, retrograde, or intracellular neuroanatomical tracer that is fixable with aldehyde-based fixatives.{27363,27362,27364} For this and other applications, biocytin is detected with avidin or streptavidin probes.  

 

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Description

A conjugate of biotin and lysine used for derivatization or conjugation to proteins and other molecules with a medium-chain length spacer; also used as an anterograde, retrograde, or intracellular neuroanatomical tracer that is fixable with aldehyde-based fixatives

Formal name: N6-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-lysine

Synonyms:  ɛ-N-(d-Biotinyl)-L-lysine

Molecular weight: 372.5

CAS: 576-19-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Affinity Probes||Research Area|Neuroscience

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