Nucleosomes are the basic repeating units of chromatin in which DNA is wrapped twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4.{17798} Peripheral proteins, including the histone H1, interact with nucleosomes to affect chromatin structure. Histones undergo many modifications, which include acetylation, methylation, and phosphorylation, that are important for the regulation of gene transcription.{17798} Histone (calf thymus) consists of a mixture of H1, H2A, H2B, H3, and H4 histones isolated from calf thymus.
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A mixture of H1, H2a, H2b, H3, and H4 histones isolated from calf thymus
Formal name: histone (cattle thymus)
Synonyms:
Molecular weight: 0
CAS: 37244-51-2
Purity:
Formulation: A crystalline solid
Application|Western Blot||Product Type|Proteins||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides
The PtdIn phosphates play an important role in the generation and transduction of intracellular signals.{8344,4096,14518} PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.
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The PtdIn phosphates play an important role in the generation and transduction of intracellular signals.{8344,4096,14518} PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.
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